What is the first dose of amiodarone during ACLS?

What is the first dose of amiodarone during ACLS?

• A. 300 mg
• B. 150 mg
• C. 100 mg
• D. 450 mg

Answer: (A)

In ACLS for a shockable rhythm like ventricular fibrillation or pulseless ventricular tachycardia, an antiarrhythmic is given after defibrillation attempts to increase the chance of return of rhythm. The first dose of amiodarone is 300 mg given quickly as an IV or IO bolus. If the rhythm recurs, a second bolus of 150 mg can be administered. After the bolus doses, a continuous infusion is started (1 mg per minute for 6 hours, then 0.5 mg per minute). The other listed amounts (100 mg or 450 mg) are not the standard initial dose.

In ACLS for a shockable rhythm like ventricular fibrillation or pulseless ventricular tachycardia, an antiarrhythmic is given after defibrillation attempts to increase the chance of return of rhythm. The first dose of amiodarone is 300 mg given quickly as an IV or IO bolus. If the rhythm recurs, a second bolus of 150 mg can be administered. After the bolus doses, a continuous infusion is started (1 mg per minute for 6 hours, then 0.5 mg per minute). The other listed amounts (100 mg or 450 mg) are not the standard initial dose.