What is the normal range for bicarbonate (HCO3) in the blood?

What is the normal range for bicarbonate (HCO3) in the blood?

• A. 34-38 mEq/L
• B. 10-14 mEq/L
• C. 22-26 mEq/L
• D. 28-32 mEq/L

Answer: (C)

Bicarbonate serves as the primary buffering substance in the blood, helping to keep the body’s pH around the normal range by balancing acids produced in metabolism. In a healthy adult, the serum concentration of bicarbonate is typically about 22 to 26 mEq/L. This range reflects normal metabolic buffering that works together with carbon dioxide to maintain stable pH, as described by the relationship between HCO3- and CO2 in acid-base balance. Values higher than this (for example, 28–32 or 34–38 mEq/L) suggest metabolic alkalosis or other issues, while values much lower (like 10–14 mEq/L) indicate metabolic acidosis or depleted buffering capacity. Therefore, 22–26 mEq/L is the best representation of normal bicarbonate levels.

Bicarbonate serves as the primary buffering substance in the blood, helping to keep the body’s pH around the normal range by balancing acids produced in metabolism. In a healthy adult, the serum concentration of bicarbonate is typically about 22 to 26 mEq/L. This range reflects normal metabolic buffering that works together with carbon dioxide to maintain stable pH, as described by the relationship between HCO3- and CO2 in acid-base balance. Values higher than this (for example, 28–32 or 34–38 mEq/L) suggest metabolic alkalosis or other issues, while values much lower (like 10–14 mEq/L) indicate metabolic acidosis or depleted buffering capacity. Therefore, 22–26 mEq/L is the best representation of normal bicarbonate levels.